diff --git a/.pep8speaks.yml b/.pep8speaks.yml
index fda26d87bf7f6..cd610907007eb 100644
--- a/.pep8speaks.yml
+++ b/.pep8speaks.yml
@@ -8,5 +8,4 @@ pycodestyle:
     ignore:  # Errors and warnings to ignore
         - E402,  # module level import not at top of file
         - E731,  # do not assign a lambda expression, use a def
-        - E741,  # do not use variables named 'l', 'O', or 'I'
         - W503   # line break before binary operator
diff --git a/setup.cfg b/setup.cfg
index 021159bad99de..516fea6213c13 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -15,7 +15,6 @@ parentdir_prefix = pandas-
 ignore =
     E402,  # module level import not at top of file
     E731,  # do not assign a lambda expression, use a def
-    E741,  # do not use variables named 'l', 'O', or 'I'
     W503,  # line break before binary operator
     C405,  # Unnecessary (list/tuple) literal - rewrite as a set literal.
     C406,  # Unnecessary (list/tuple) literal - rewrite as a dict literal.